Life Uninterrupted: A New Dialysis Solution
Nephrodite is the first to develop an implantable dialysis platform that continuously filters a patient’s blood while delivering new levels of independence and mobility for eligible patients with end-stage kidney disease.
Holly™ is an investigational device and is not yet approved for commercial use.
Freedom
Dignity
Mobility
Simplicity
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For 70+ years, dialysis has taken too much from patients
For nearly 3.5 million people worldwide, end-stage kidney disease means hundreds of hours each year spent in dialysis chairs. Jobs are lost, weddings missed, and quality of life devastated.
Three times a week, patients endure painful treatment and disruptive scheduling, while potential long-term complications and immense costs offer little meaningful improvement in quality of life.
- 600–800+ hours every year spent in a dialysis chair
- Loss of independence, dignity, and everyday mobility
- Repeated needle sticks heighten risks of infection, stenosis, and thrombosis
- Approximately $100B in annual costs borne by Medicare and other payers
Introducing Holly™ by Nephrodite: Designed for how patients deserve to live.
Holly™ by Nephrodite is an implantable, continuous dialysis system with a simple external connector, designed as a true kidney replacement therapy alternative.
Inspired by a young woman who persevered for years with kidney failure, Holly reflects Nephrodite’s promise to improve lives for people with kidney disease.
- One-time surgical implant
- No arm grafts, fistulas, or external vascular access
- Discreet lower abdominal catheter for at-home or on-the-go dialysis
- Cartridge-based membrane system for scheduled replacement
- Designed to function like a healthy kidney—ensuring balanced blood chemistry
Holly delivers a next-generation portable hemofiltration system powered by our proprietary membrane platform and edge computing technology
Its core architecture can also be applied to liver and metabolic toxin management, critical care including military settings, and long-duration spaceflights or extreme environments.
Holly™ is an investigational device and is not yet approved for commercial use.
Physician-led, patient-guided and mission-driven
The Nephrodite Team
Nephrodite is led by surgeons, scientists and engineers who dedicated their careers to evolving kidney care to meet the real world needs and support the human dignity of patients.
Instead of optimizing 70-year-old technology for marginal gains, the cross-discipline team applies their expertise to reinvent the kidney care model, guided by patient and provider insights at every turn.
Our goal is now focused on reaching human patients to finally end the stagnation in dialysis and deliver a better, life-improving option for kidney care.
Our name, Nephrodite, originated from the combination of Nephros, which means kidney, and Aphrodite, the symbol of creation and renewal. The name embodies our vision to transform kidney care through innovation, ingenuity and a shared purpose to improve patients’ quality of life.
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